01.07.2019 - 30.06.2021
The main goal of the iNano project is the development of a new synthesis approach for indium phosphide-based semiconductor nanocrystals. The unique properties of these NCs will be used to gain a better understanding of the neurocognitive proc. in the brain.
Bundesanstalt für Materialforschung und -prüfung
iNano – Inverted core/shell nanocrystals: The future nanomaterial for the visualization of neuron activity
The overall aim of the iNano project is to develop a new synthesis approach for the preparation of InP NCs, which will be used to record and stimulate neuron activity in dorsal root ganglion neuron cells. Highlights are the first preparation of rod-shaped InP NCs, their complete optoelectronic characterization on the ensemble and single-particle level, and their utilization in in vitro imaging under one and two-photon excitation. First, these NCs will be incubated with the dorsal root ganglion neuron cells and changes of the NCs photoluminescence intensity used to measure the neuron activity. Second, the created dipole moment after NCs excitation with light will be used to stimulate an action potential via depolarization of the neuron cell surface.